American Journal of Innovative Research & Applied Sciences
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American Journal of innovative Research & Applied Sciences
ISSN 2429-5396 (Online) OCLC Number: 920041286
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| APRIL | VOLUME 4 | N° 4 | 2017 |
ABSTRACT Background: Renal hemodialysis requires enormous amounts of water for functioning. In order to avoid complications with patients’ blood, this water must be treated. The objectives of this study were to investigate chemical and microbial contamination of treated water, to evaluate the disinfection protocol applied and the double reverse osmosis installation, and to determine the effect of double reverse osmosis on the patient’s inflammatory status. Methods: Our study was done at the Al Ghassani hospital hemodialysis unit’s. Samples were taken at the old and new units. The chemical and microbiological analyses were performed according to national standards. Non-compliance was determined by comparing the results with the values reported by national guidelines. The CRP was determined by the Immuno turbudimetrie-test. Results: Non conformity caused by nitrates, pH and conductivity was observed both in a few samples before disinfection and introduction of the double reverse osmosis. Treated water and dialysates showed counts of heterotrophic bacteria lower than 100 CFU/ml. Statistically significant difference between treated water analyzed before disinfection and those evaluated after disinfection, was observed only in new unit (p=0.047). We noted statically significant differences in contamination level between the first and second period both in starting loop (p=0.002), dialysate (p=0.004), and in C-reactive protein level (p=0.007). Conclusions: Non-compliance of chemical results was observed both before disinfection and after introduction of the double reverse osmosis. However, Microbial results are in accordance with national standards for dialysis water. The implementation of double reverse osmosis in the new unit showed a highly significant improvement. Keywords: Dialysate Fluid Compatibility , Quality, Hemodialysis Delivery Systems, Inflammation, Quality Improvement, Water Treatment.
1. LANENC Laboratory | Faculty of Sciences Dhar ElMahraz | Sidi Mohammed ben Abdellah University | Fez | Morocco| 2. Regional Diagnostic Laboratory Epidemiological and Environmental Health | Regional Health Directorate | Fez | Morocco | 3. Higher Institute of Nursing and Technical Occupations Health | Fez | Morocco | 4. Higher Institute of Nursing and Technical Occupations Health | Meknes | Morocco | 5. Microbiology Laboratory | Faculty of Medicine and Pharmacy | Sidi Mohammed ben Abdellah University |Fez| Morocco| 6. Hemodialysis Unit | Al Ghassani hospital | Morocco | 7. Epidemiological Laboratory | Faculty of Medicine and Pharmacy | Sidi Mohammed ben Abdellah University |Fez| Morocco | 8. Nephrology Department | Hassan II University Hospital | Faculty of Medicine and Pharmacy | Sidi Mohammed ben Abdellah University | Fez | Morocco |
This article is made freely available as part of this journal's Open Access: ID | Sanae ManuscriptRef.4-ajiras080417|
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