ABSTRACT

Background: The major problem today for osteoporosis is to correctly identify patients at high risk for fracture requiring effective preventive treatment. The need also is to develop well-defined therapeutic strategy. Objective: This study aims to improve our understanding of osteoporosis, a disease that can now be prevented and treated. By studying the risk factors and the influence of osteoporosis induced by glucocorticoids in patients and assessing the perception of glucocorticoid-induced osteoporosis in Moulay Youssef hospital in Rabat, Morocco. Methods: This study took place in a hospital structure in 2015 in Moulay Youssef hospital in Rabat, Morocco The information about hospital patients were collected using a questionnaire and individual interviews with general practitioners, cardiologists, pulmonologists, and surgeons, the results are given in tables and figures. A descriptive statistical analysis was carried. The data collection method is represented by: a). a survey conducted using an anonymous questionnaire distributed to individual patients.and b). a semi directive interview with general practitioners, cardiologists, pulmonologists, and surgeons. Data analysis was performed by a statistical descriptive analysis and and a quantitative analysis which was based primarily on a semi-structured interview. Results:. The study sample consists of all hospitalized patients and those who came in consultation; it consists of 100 patients, 46 men (46%) and 54 women (54%), the average age is between 30 and 60 years and older. 93% consider menopause one of the risk factors for osteoporosis, 85% blame the low calcium diet and low sun exposure. 78% emphasized the fracture risk of osteoporosis. 91% ignores the recommended intake of calcium daily. 54% of participants surveyed were menopausal, 62% did not practice physical activity. 46% receiving corticosteroids, the size of 64% of study participants decreased by 3cm, 94% of participants did not have densitometry check up and 97% have never received anti-ostéosporosis treatment. Accurate and early identification of patients at high risk of fracture, avoids the adverse effects of osteoporotic fractures. Simple tools need to be developed according to a well-defined therapeutic strategy. Conclusion: It appears that in osteoporosis fracture event is one of the most dreaded complications of corticosteroid therapy at a dose beyond 5 mg / d of prednisone equivalent for a period exceeding 3 months. Some authors have reported the existence of a fracture risk of lower dose for three months or more.

Keywords: Glucocorticoid-induced osteoporosis, fracture risk, densitometry, bone mass density, therapeutic strategy, corticosteroids.