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American Journal of innovative
Research & Applied Sciences

ISSN 2429-5396 (Online)
OCLC Number: 920041286

| DECEMBER | VOLUME 9 | N° 6 | 2019 |

| Info-AJIRAS-® Journal ISSN 2429-5396 (Online) / Reference CIF/15/0289M |

American Journal of Innovative Research & Applied Sciences

Authors Contact

| Casimir Dewanou Akpovi ^1,* | and| Antoine Fandohan ²|

Affiliation.

^1.Unité de Recherche sur les Maladies Non Transmissibles et le Cancer (UR-MNTC) | Laboratoire de Rechercher en Biologie Appliquée (LARBA) | Ecole

Polytechnique d’Abomey-Calavi | Université d’Abomey-Calavi | EPAC (UAC), 01BP 2009 Cotonou | Benin |

^2.Organisation Non Gouvernementale (ONG) Creuset d’Informations et d’Assistance Communautaire (CIACO BENIN) | Cotonou | Bénin |

This article is made freely available as part of this journal's Open Access: ID | Casimir-Ref.1-ajira071219 |

ABSTRACT

Background: The prevalence of sickle cell trait carriers (AS) is about 30% in some areas of Intertropical Africa and 40% in Central Africa. In Benin, the prevalence of sickle cell trait was estimated at 24%, of which 4.8% had the severe form of the hemoglobinopathy. Despite these alarming statistics, consequent preventive measures are slow to materialize. The present study aimed to develop a strategy for population sensitizing on Sickle Cell Disease (SCD). Methods: The study was carryout in the commune Sô-Ava in southern Benin. It is a lacustrine town of 218 km² with 118.497 populations. Samples were collected in EDTA. Hemoglobin in the sample was separated by electrophoresis and resulting patterns were scanned on a scanning densitometer. ABO blood groups were determined manually using monoclonal anti-A and anti-B. Results: A pictogram called "Drepastop" was made and used for results expression. Of the 6156 participants, 4403 (71.52%) were non-carriers of SCD traits, 1624 (26.38%) were heterozygous and 129 (2.10%) were homozygous. Of the 1624 heterozygous subjects, 1140 (18.52%) were AS and 484 (7.86%) AC. Among homozygous SCD carriers, 71 (1.15%) were SC, 39 (0.63%) SS and 19 (0.32%) CC. The majority of the study participants, 3167 (51.44%) were blood group O, followed by 1499 (24.35%) group B, 1239 (20.13%) blood group A and 251 (04.08%) blood group AB. Conclusion: The study provided 4403 Green/Green card, 1140 Green/Red, 484 Green/Yellow, 71 Red/Yellow, 39 Red/Red and 19 Yellow/Yellow to the population of Sô-Ava. Our innovation has helped to raise awareness and demystify sickle cell disease. It allowed the population to link "Drepastop" to the choice of spouse.
Keywords: Sickle Cell Disease, pictogram, prevention, Drepastot, Benin.

*Corresponding author Author & Copyright Author © 2019: | Casimir Dewanou Akpovi | . All Rights Reserved. All articles published in American Journal of Innovative Research and Applied Sciences are the

property of Atlantic Center Research Sciences, and is protected by copyright laws CC-BY. See: http://creativecommons.org/licenses/by-nc/4.0/

A PICTOGRAM INNOVATION FOR SICKLE CELL DISEASE PREVENTION IN BENIN, DREPASTOP

| Casimir Dewanou Akpovi ^1,* | and | Antoine Fandohan ² |. Am. J. innov. res. appl. sci. 2019; 9(6): 434-438.